I.29 Pituitary adenoma

PI29b2 - Click here to make me bigger
PI.29.b2 Chromophobe pituitary adenoma (MT x16). Small tumour (diameter 2 mm) discovered at autopsy. Compared to the surrounding pituitary tissue, this tumour nodule is more cellular and has a much less apparent vascular network because its vessels have a thin, rudimentary wall poor in collagen. The result is attenuation of the microlobular architecture, which is well demonstrated in the normal pituitary by a reticulin impregnation technique. Microadenomas are defined radiologically as small intrapituitary tumours with a diameter under 10 mm. They can be chromophobe or not, secretory or not.